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Cannabis as Medicine? Overview

It is utterly mind-blowing that people have no idea that Cannabis has been part of the medical prescription landscape for over 20 years. That’s right T. G. A (Therapeutic Goods Administration) trialled and approved cannabis based medicines have been available as an option to alleviate, if only in small ways, some of the symptoms of a couple of diseases or help with recovery from treatment. However, the claims of this plant being a ‘miracle cure’ for just about everything, have existed for of 100 years… yet in no credible and advanced research has any of the properties of the Cannabis plant ‘cured’ anything, ever!

There is no argument that some components of this incredibly complex plant can have some therapeutic benefit, be it ever so small, but deriving such from the plant with out co-opting some of the more detrimental components has proven incredibly difficult. On top of that, the evidence emerging from latest science, sees that some of these therapies, do more harm than good, with the temporary alleviating of a symptom on one hand, and incurring along term genetic harm on the other!

Again if facts and evidence matter to your best-practice health care, then this is the space for you. Make informed decisions based on science, and not quackery!

In addition to its acute effects, cannabis/THC induces epigenetic modifications, which can affect its consumers and their offspring.


Summary: Epigenetics causes changes in the phenotype in the absence of changes in the DNA of genes, i.e., the genotype. Under various influences, such as exposure to certain xenobiotics, epigenetic marks are produced by different mechanisms, including the grafting of methyl groups onto certain cytosines of DNA, or on diaminated acids of histones, or the grafting of acetyl groups onto these histones around which the DNA of genes is wrapped. These modifications affect the exposure of these DNA segments to RNA polymerases that copy it into messenger RNAs, resulting in the carrier proteins of each of our traits. As a result, the expression of these genes can be repressed or increased. Tetrahydrocannabinol/THC, the major psychotropic and addictive principle of cannabis, induces epigenetic effects in its users that can have a lasting effect on some of their characteristics. If they are of childbearing age or if they are pregnant women, they will be able to pass on these epigenetic marks to their offspring. This transmission may result in malformations of the conceived child, reductions in height and birth weight, delayed development of staturoweight and mental health, increased risk of sudden death, hyperactivity with attention deficit, vulnerability to autism, drug addiction, depressive disorders, schizophrenia, cognitive disorders, etc. immune deficiencies.

(Source: Bulletin of the National Academy of Medicine Volume 208, Issue 4, April 2024, Pages 459-465 as publish in Science Direct)

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