Youth are becoming addicted to marijuana at nearly the same rates as prescription opioids.

Teenagers’ cannabis addiction rates are about the same as those for prescription opioids, according to a new study published in JAMA Pediatrics.  The JAMA study is based on data from the three-year span between 2015 to 2018 that was collected by national surveys done conducted by the U.S. Department of Health and Human Services.

The research team explained, “Earlier age at drug initiation has been shown to be associated with faster transition to substance use disorder (SUD).  However, prevalence of specific SUDs as a function of time since first substance use among young people has not, to our knowledge, been investigated.  We examined the prevalence of specific SUDs since first drug use (including tobacco, alcohol, cannabis, cocaine, methamphetamine, and heroin) or prescription misuse (including opioids, stimulants, and tranquilizers) in adolescents aged 12 to 17 years and young adults aged 18 to 25 years.”

They concluded, “A year after first trying cannabis, almost 10.7 per cent of adolescents age 12 to 17 met the criteria of addiction.  Those in the same age group who tried prescription opioids had a similar addiction rate of 11.2 per cent.”

Nora Volkow, an author of the JAMA study and the current director of the U.S.’s National Institute on Drug Abuse, said, “The findings contradict widely held perceptions that cannabis isn’t particularly addictive and may attract attention amid a broad U.S. push to liberalize its use.  The rates of addiction were significant, especially since teenagers’ brains are still developing…One in 10 teens having a marijuana addiction — that’s huge.  Using cannabis also gives them a higher chance of becoming addicted to other drugs later.”

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For complete article Cannabis Almost As Addictive as Opioids, JAMA Study Finds - (legalreader.com)

Younger age of first cannabis use or prescription drug misuse is associated with faster development of substance use disorders

A new study shows that in the time after first trying cannabis or first misusing prescription drugs, the percentages of young people who develop the corresponding substance use disorder are higher among adolescents (ages 12-17) than young adults (ages 18-25). In addition, 30% of young adults develop a heroin use disorder and 25% develop a methamphetamine use disorder a year after first using heroin or methamphetamine. These findings, published in JAMA Pediatrics, emphasize the vulnerability of young people to developing substance use disorders.

The younger the initiation to substance use - of any drug - the greater the risk of addiction! This is not news for anyone caring to spelunk the already overwhelming data of drug use impact on the emerging adult.

There is no credible voice in the literature that is denying that there is NO SAFE use of any psychotropic toxin (alcohol included) for the developing brain – up to 25-30 years of age.

Beyond any obvious harms incurred, evidence continues to mount as to the exacerbated risk of developing Substance Use Disorders (SUD). This, of course, is horrendous for anyone, but even more so for the developing brain cohort.

The 'walking back out' of this damaged space is incredibly difficult, and the lost time, potential, capacity, and agency of that drug use experimenting youth cannot really be quantified.

This is yet another vital reason not to increase permission models in relation to Drugs of Dependence. A culture that sets in motion mechanisms that increase access, availability and/or acceptability of drug use, is a 'careless' culture and the intergenerational harms this also facilitates, lands at the feet of those who promote such recklessness.

It's time we stopped this current ‘War FOR Drugs’ and focused, as we did with the anti-smoking QUIT campaign, on preventing, not promoting uptake. One Focus – Once Message – One Voice in all sectors of the community, all focusing on emphasising protective and resiliency building factors into our communities and their families, not demolishing them.

 #DemandReduction #prevention #resilience

For complete article go to National Institute of Health -  Younger age of first cannabis use or prescription drug misuse is associated with faster development of substance use disorders | National Institutes of Health (NIH)

 

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Also See Drug Policy: Building or Demolishing Community Resilience?

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Cannabidiol Shows Promise as a Treatment for Cannabis Use Disorder: Boston University School of Medicine

Oh, the Irony! Of course, in the naturally occurring and naturally growing, non-engineered cannabis plant (which no longer exists on the planet - other than perhaps in regions not yet traversed by humans) Cannabidiol (CBD) is the naturally occurring agonist to the psychosis inducing THC compound in cannabis. Naturally growing cannabis historically had around 2% THC, with naturally occurring CBD ‘tempering’ the psychoactive properties of THC.

This investigation into this particular therapeutic potential, is just that, only a potential. However, with the growing research on the negatives of CBD, this may also prove ‘one step forward and two back?’

However, the breathtaking (pardon the pun) irony of all this is that the industry sells you the psychosis inducing cannabis product, then when you are dependent, sells you the 'helper' to manage it – making money going into the user stream, and making money while you attempt to exit the user stream.   

Great business model! Especially for the addition for profit industry that is.

What action negates this entire mess? Not using in the first place! But apparently that is not an option in our public and mental health ‘advancing’, yet drug permitting culture?

For considerably more research go to Cannabis As Medicine Resource Library

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The industry lacks randomized controlled clinical trials that can clearly establish benefits and risks.

By ©  Jane E. Brody March 8, 2021

…. of the same health concerns raised decades ago about using marijuana therapeutically are still unresolved, even as the potency of the plant’s intoxicating ingredient, tetrahydrocannabinol, best known as THC, has increased fivefold. Furthermore, exclusive medical use is uncommon; in a Canadian study of 709 medical users, 80.6 percent also reported using marijuana recreationally.

“People are using a medical excuse for their recreational marijuana habit,” said Dr. Kenneth Finn, a pain management specialist in Colorado Springs and editor of a new, 554-page professional book on the subject, “Cannabis in Medicine: An Evidence-Based Approach.”

The evidence — or lack thereof — of health benefits that can be reliably attributed to smoking, vaping or ingesting marijuana, even in its purest form, is described in great detail in Dr. Finn’s book. “Components of the cannabis plant can help in various conditions, but that’s not what people are buying in stores,” he said in an interview. “Let’s do the research on purified, natural, noncontaminated cannabinoids,” as the various potentially therapeutic chemicals in marijuana are called.

Three such substances have been approved by the Food and Drug Administration. One, Epidiolex, a cannabidiol-based liquid medication, is approved to treat two forms of severe childhood epilepsy. The others, dronabinol (Marinol, Syndros) and nabilone (Cesamet), are pills used to curb nausea in cancer patients undergoing chemotherapy and to stimulate appetite in AIDS patients with wasting syndrome.

Another marijuana-based drug, nabiximols (Sativex), is available in Canada and several European countries to treat spasticity and nerve pain in patients with multiple sclerosis.

Medicinal cannabis is hardly a new therapeutic agent. It was widely used as a patent medicine in the United States during the 19th and early 20th centuries and was listed in the United States Pharmacopoeia until passage of the Marijuana Tax Act in 1937 rendered it illegal.

Then a federal law in 1970 made it a Schedule 1 controlled substance, which greatly restricted access to marijuana for legitimate research. Also complicating attempts to establish medical usefulness is that plants like marijuana contain hundreds of active chemicals, the amounts of which can vary greatly from batch to batch. Unless researchers can study purified substances in known quantities, conclusions about benefits and risks are highly unreliable.

That said, as recounted in Dr. Finn’s book, here are some conclusions reached by experts about the role of medical marijuana in their respective fields:

CannabisInMedicineBOOK

Pain Management: People using marijuana for pain relief do not reduce their dependence on opioids. In fact, Dr. Finn said, “patients on narcotics who also use marijuana for pain still report their pain level to be 10 on a scale of 1 to 10.” Authors of the chapter on pain, Dr. Peter R. Wilson, pain specialist at the Mayo Clinic in Rochester, Minn., and Dr. Sanjog Pangarkar of the Greater Los Angeles V.A. Healthcare Service, concluded, “Cannabis itself does not produce analgesia and paradoxically might interfere with opioid analgesia.” A 2019 study of 450 adults in the Journal of Addiction Medicine found that medical marijuana not only failed to relieve patients’ pain, it increased their risk of anxiety, depression and substance abuse.

Multiple Sclerosis: Dr. Allen C. Bowling, neurologist at the NeuroHealth Institute in Englewood, Colo., noted that while marijuana has been extensively studied as a treatment for multiple sclerosis, the results of randomized clinical trials have been inconsistent. The trials overall showed some but limited effectiveness, and in one of the largest and longest trials, the placebo performed better in treating spasticity, pain and bladder dysfunction, Dr. Bowling wrote. Most trials used pharmaceutical-grade cannabis that is not available in dispensaries.

Glaucoma: The study suggesting marijuana could reduce the risk of glaucoma dates back to 1970. Indeed, THC does lower damaging pressure inside the eye, but as Drs. Finny T. John and Jean R. Hausheer, ophthalmologists at the University of Oklahoma Health Sciences Center, wrote, “to achieve therapeutic levels of marijuana in the bloodstream to treat glaucoma, an individual would need to smoke approximately six to eight times a day,” at which point the person “would likely be physically and mentally unable to perform tasks requiring attention and focus,” like working and driving. The major eye care medical societies have put thumbs down on marijuana to treat glaucoma.

Mental Health: Allison Karst, a psychiatric pharmacy specialist at the V.A. Tennessee Valley Healthcare System, who reviewed the benefits and risks of medical marijuana, concluded that marijuana can have “a negative effect on mental health and neurological function,” including worsening symptoms of PTSD and bipolar disorder.

Dr. Karst also cited one study showing that only 17 percent of edible cannabis products were accurately labeled. In an email she wrote that the lack of regulation “leads to difficulty extrapolating available evidence to various products on the consumer market given the differences in chemical composition and purity.” She cautioned the public to weigh “both potential benefits and risks,” to which I would add caveat emptor — buyer beware.

For complete article go to © NYTimes https://www.nytimes.com/2021/03/08/well/live/medical-marijuana.html

Handbook CannabisPathologies

A Review of Cases of Marijuana and Violence - Research (March 2020) 

Abstract: Marijuana is the most consumed illicit drug in the world, with over 192 million users. Due to the current legalization push of marijuana in the United States, there has been a lack of oversight regarding its public health policies, as marijuana advocates downplay the drug’s negative effects. This paper’s approach is from a public health perspective, focusing specifically on the cases of violence amongst some marijuana users.

Here, we present 14 cases of violence with chronic marijuana users that highlight reoccurring consequences of: marijuana induced paranoia (exaggerated, unfounded distrust) and marijuana induced psychosis (radical personality change, loss of contact with reality). When individuals suffering from pre-existing medical conditions use marijuana in an attempt to alleviate their symptoms, ultimately this worsens their conditions over time. Although marijuana effects depend on the individual’s endocannabinoid receptors (which control behavioral functions, like aggression) and the potency level of tetrahydrocannabinol (THC) in the drug, scientifically documented links between certain marijuana users and violence do exist. Wider public awareness of the risks and side effects of marijuana, as well as a more prudent health policy, and government agency monitoring of the drug’s composition, creation, and distribution, are needed and recommended.

Introduction: In the United States, ten states have legalized the recreational use of marijuana and over 20 states have decriminalized the recreational use of it. Recent reports suggest, however, that the increase of the recreational use of marijuana is causing detrimental effects to individuals, as well as the society as a whole [1,2,3].

These effects include, but are not limited to, the increase of violence, the increase of thriving underground marijuana markets, and increase in car accident claims after the legalization of marijuana where the recreational use of marijuana was legalized [1,2,3]. This is caused by lack of oversight. Marijuana is being legally sold with high THC concentration levels without taking into account its addictive qualities and adverse effects. On the other hand, and contrary to popular belief, marijuana is still illegal in the Netherlands and it is decriminalized. However, the consumption and storage of marijuana are limited by law and the approach taken by the Netherlands is to decriminalize the drug in order to be able to help individuals struggling with marijuana use. This prudent oversight has resulted in a decreased in violence and people are able to get the care they need to deal with addiction and become less prone to violence [1,2,3].

Furthermore, the consumption of marijuana is associated with an increase in violent behavior over the course of an individual’s lifespan, a high risk of psychosis for frequent users, an increase of cardiovascular diseases, and deterioration in health for individuals who have pre-existing mental health issues such as Post Traumatic Stress Disorder, social anxiety, and depression [4,5,6].

According to research studies, marijuana use causes aggressive behavior, causes or exacerbates psychosis, and produces paranoia. These effects have been illustrated through case studies of highly publicized incidents and heightened political profiles.

These cases contain examples of repeated illustrations of aggression, psychosis and paranoia by marijuana users and intoxication. Ultimately, without the use and intoxication of marijuana, the poor judgment and misperceptions displayed by these individuals would not have been present, reducing the risk for actions that result in senseless deaths.

For full research go to https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084484/

(The mounting anecdotal evidence of this growing and pervasive reality are recorded at Attacker Smoked Cannabis: suicide and psychopathic violence in the UK and Ireland – "Those whose minds are steeped in cannabis are capable of quite extraordinary criminality.")

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