{"id":2394,"date":"2020-01-28T09:42:24","date_gmt":"2020-01-27T22:42:24","guid":{"rendered":"https:\/\/www.dalgarnoinstitute.org.au\/wp_site\/adolescent-cannabis-exposure-increases-heroin-reinforcement-in-rats-genetically-vulnerable-to-addiction\/"},"modified":"2025-11-12T21:02:10","modified_gmt":"2025-11-12T10:02:10","slug":"adolescent-cannabis-exposure-increases-heroin-reinforcement-in-rats-genetically-vulnerable-to-addiction","status":"publish","type":"post","link":"https:\/\/www.dalgarnoinstitute.org.au\/wp_site\/adolescent-cannabis-exposure-increases-heroin-reinforcement-in-rats-genetically-vulnerable-to-addiction\/","title":{"rendered":"Adolescent Cannabis Exposure Increases Heroin Reinforcement In Rats Genetically Vulnerable To Addiction"},"content":{"rendered":"<p><strong>Highlights<\/strong><\/p>\n<ul>\n<li>Genetic background affects the outcome of adolescent cannabis exposure<\/li>\n<li>THC exposure increases heroin reinforcing properties in LEW addiction prone rats<\/li>\n<li>LEW, but not F344 rats, show increased motivation for heroin following THC<\/li>\n<li>THC exposure increases reinstatement by cues in F344 and by priming in LEW rats<\/li>\n<li>A common liability mechanism might be at the basis of THC gateway effect<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002839082030040X\" target=\"_blank\" rel=\"noopener\">https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S002839082030040X<\/a>&nbsp;(2020)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Highlights Genetic background affects the outcome of adolescent cannabis exposure THC exposure increases heroin reinforcing properties in LEW addiction prone rats LEW, but not F344 rats, show increased motivation for heroin following THC THC exposure increases reinstatement by cues in F344 and by priming in LEW rats A common liability mechanism might be at the 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