Cannabis as Medicine

Cannabis Legalization and Opioid Use Disorder in Veterans Health Administration Patients

Abstract Importance: In the context of the US opioid crisis, factors associated with the prevalence of opioid use disorder (OUD) must be identified to aid prevention and treatment. State medical cannabis laws (MCL) and recreational cannabis laws (RCL) are potential factors associated with OUD prevalence. Objective: To examine changes in OUD prevalence associated with MCL and RCL

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Therapeutic Use of Cannabis: What Healthcare Professionals Need to Know About Risks

The therapeutic application of cannabis has become increasingly prevalent across developed nations, yet the scientific evidence supporting its medical use remains surprisingly limited. A recent JAMA Clinical Reviews podcast featuring Dr Kevin Hill from Harvard Medical School reveals critical information that healthcare professionals and patients need to understand about the therapeutic use of cannabis and

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Cannabis Therapeutic Evidence: Separating Scientific Facts from Marketing Claims

Recent national policy changes have made cannabis increasingly available for medical purposes across numerous conditions. Yet a significant gap exists between what’s approved for cannabis therapeutic use and what scientific evidence actually supports. Understanding this distinction is crucial for public health and informed decision-making. The FDA Approval Reality for Cannabis Therapeutic Use Despite widespread availability

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Cannabis Use in Older Adults: Five Critical Health Facts from Medical Experts

Cannabis Use in Older Adults: Five Critical Health Facts from Medical Experts    As medical and recreational cannabis becomes increasingly accessible across the United States and beyond, a growing number of older adults are turning to marijuana for relief from chronic pain, insomnia, and anxiety. However, medical experts are raising urgent concerns about the unique

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Cannabis & Pain –  Placebo Response and Media Attention in Randomized Clinical Trials Assessing Cannabis-Based Therapies for Pain: A Systematic Review and Meta-analysis

  Key Points Question  What is the size of the placebo response in cannabinoid trials for clinical pain, and is the magnitude of placebo response associated with media attention on the trials? Findings:  This meta-analysis of 20 studies of 1459 individuals found a significant pain reduction in response to placebo in cannabinoid randomized clinical trials. Media attention

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Cannabis Use Linked to Chromosomal Damage in Embryos and Reduced Fertility, New Research Reveals

  Mounting scientific evidence continues to challenge the narrative that cannabis is a harmless substance, with alarming new research demonstrating significant THC effects on fertility and embryonic development. A groundbreaking study conducted by researchers in Canada and Israel has uncovered disturbing links between THC exposure and chromosomal abnormalities in human embryos created through IVF. The

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Cannabis as Pain Management? Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study

  Interest in the use of cannabis and cannabinoids to treat chronic non-cancer pain is increasing, because of their potential to reduce opioid dose requirements. We aimed to investigate cannabis use in people living with chronic non-cancer pain who had been prescribed opioids, including their reasons for use and perceived effectiveness of cannabis; associations between

Cannabis as Pain Management? Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study Read More »

Leading Medical Body Issues Universal Screening Recommendation Against Cannabis Use in Pregnancy

The American College of Obstetricians and Gynaecologists (ACOG) has issued decisive new clinical guidance declaring there is no safe level of marijuana during pregnancy and recommending universal screening for cannabis use throughout pre-pregnancy, pregnancy, and postpartum periods. The authoritative medical organisation’s statement directly challenges the increasingly prevalent misconception that cannabis represents a safe or beneficial

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TGA Medicinal Cannabis submission

This document addresses three of the TGA (Therapeutic Goods Administration) 2025 consultation questions: 1. Contraindications for medical cannabis – see Appendix A 2. Claims for medical cannabis not supported by rigorous science – See Appendix B 3. Lack of quality assurance in the production of medicinal cannabis – See Appendix C   View Document

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Cannabis impacts female fertility as evidenced by an in vitro investigation and a case-control study

Abstract: Cannabis consumption and legalization is increasing globally, raising concerns about its impact on fertility. In humans, we previously demonstrated that tetrahydrocannabinol (THC) and its metabolites reach the ovarian follicle. An extensive body of literature describes THC’s impact on sperm, however no such studies have determined its effects on the oocyte. Herein, we investigate the impact

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