Cannabis as Medicine

Prenatal delta-9-tetrahydrocannabinol exposure is associated with changes in rhesus macaque DNA methylation enriched for autism genes Abstract Background: With the growing availability of cannabis and the popularization of additional routes of cannabis use beyond smoking, including edibles, the prevalence of cannabis use in pregnancy is rapidly increasing. However, the potential effects of prenatal cannabis use on

In addition to its acute effects, cannabis/THC induces epigenetic modifications, which can affect its consumers and their offspring. https://doi.org/10.1016/j.banm.2024.02.009 Summary: Epigenetics causes changes in the phenotype in the absence of changes in the DNA of genes, i.e., the genotype. Under various influences, such as exposure to certain xenobiotics, epigenetic marks are produced by different mechanisms,

CBD is now a widely sold supplement in oils, vapes, weed gummies, and drinks at local supermarkets Trendy cannabidiol products such as CBD gummies and oils are a waste of money and even potentially harmful, according to Oxford scientists. Researchers analysed 16 clinical trials and found that in 15 of them, the use of CBD was no better than

When you have ‘formulations’ not pharmaceuticals being peddled as medicine, then recreational cannabis use is easy to ‘hide’. In fact it was a key strategy of pro-cannabis lobby to get legalisation for recreational use of the highly engineer drug. (Source: SBS Story here)   Also see Cannabis as ‘Medicine?’: Pot Propaganda, Emotive Anecdote, Marketing Manipulation, and the

Question:  What is the risk of developing schizophrenia spectrum disorder following an emergency department (ED) visit caused by substance use with and without psychosis? Findings:  In this cohort study of 9.8 million people, individuals with an ED visit for substance-induced psychosis or substance use without psychosis were at increased risk of developing schizophrenia spectrum disorder within 3

Research team discovered that individuals who used cannabis long–term (for several years or more) and heavily (at least weekly, though a majority in their study used more than four times a week) exhibited impairments across several domains of cognition. Long–term cannabis users’ IQs declined by 5.5 points on average from childhood, and there were deficits in learning and processing speed compared to people that did not use cannabis…The study also

Cannabis use disorder contributes to cognitive dysfunction in Veterans with traumatic brain injury. Background: While emerging evidence supports a link between traumatic brain injury (TBI) and progressive cognitive dysfunction in Veterans, there is insufficient information on the impact of cannabis use disorder (CUD) on long-term cognitive disorders. This study aimed to examine the incidences of cognitive

Yet another study confirms that cannabis is not an effective treatment for opioid addiction, this time from Brazil’s University of Ribeirão Preto, Yale University et al. Their meta review covered 8,367 people given drugs to treat opioid addiction. Conclusion: There was no significant association between cannabis use and non-medical opioid use among patients receiving pharmacotherapies for OUD See