Cannabis Conundrum

Cannabis & Children’s Cancer: A geospatiotemporal and causal inference epidemiological exploration of substance and cannabinoid exposure as drivers of rising US pediatric cancer rates Affiliations expand  DOI: 10.1186/s12885-021-07924-3 Abstract Background: Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975-2015 for unknown reasons. Prenatal cannabis exposure has been linked with several pediatric cancers which together comprise the

Moore and colleagues9 … found that individuals who had used cannabis had a significant, 1.4-fold increased risk of any psychotic outcomes, independent of potential confounding and transient intoxication effects. Findings also provided evidence for a dose-response effect, with even greater, 2.1-fold risk in individuals who used cannabis most frequently. More recently, Marconi and colleagues10 performed a meta-analysis

Abstract Introduction: This paper compares consequences of cannabis use initiated after high school with those of cannabis initiation in adolescence, with estimates of the proportion of adverse consequences accounted for by adult-onset and adolescent-onset cannabis users. Methods: A state-representative sample in Victoria, Australia (n = 1792) participated in a 10-wave longitudinal study and was followed from age

Is weed a gateway drug at any age? Frequent users are three times more likely to be heavy drinkers and 20 TIMES more likely to use other drugs – no matter when they start smoking marijuana Researchers compared people who began regularly using marijuana as teenager and as adults to non-users  People who began using

Highlights Peer deviance is associated with higher odds of cannabis use. PRS is associated with higher odds of cannabis use among subjects who never engage with community activities. Analyses in African American subjects were inconclusive due to limited portability of the PRS. Church activities is associated with lower odds of cannabis use. Abstract Background: Among

JAMA Pediatr. Published online January 19, 2021. doi:10.1001/jamapediatrics.2020.5494 Question  Is cannabis use disorder associated with heightened risk of self-harm, suicide, and mortality among youths with mood disorders? Findings  This population-based cohort study of Medicaid-enrolled youths with mood disorders found that the presence of cannabis use disorder was significantly associated with an increased risk of nonfatal self-harm, all-cause mortality,

50% of U.S. teens who use marijuana on a regular basis admit to driving while high, according to a new study published in JAMA Network Open.  The reach these findings, researchers looked at data from the 2017 Youth Risk Behavior Survey. “Marijuana can impair cognitive abilities that are critical for safe driving,” the study’s lead researcher Dr. Motao Zhu, an associate professor of

Background: Whilst many studies have linked increased drug and cannabis exposure to adverse mental health (MH) outcomes their effects on whole populations and geotemporospatial relationships are not well understood. Conclusion: Data show all four indices of mental ill-health track cannabis exposure across space and time and are robust to multivariable adjustment for ethnicity, socioeconomics and

Cannabinoids Exacerbate Alcohol Teratogenesis (Alcohol & Cannabis Toxic Combination for Developing Babies) Scientific Reports volume 9, Article number: 16057 (2019) Abstract: We tested whether cannabinoids (CBs) potentiate alcohol-induced birth defects in mice and zebrafish, and explored the underlying pathogenic mechanisms on Sonic Hedgehog (Shh) signaling. The CBs, Δ9-THC, cannabidiol, HU-210, and CP 55,940 caused alcohol-like

 Abstract Objective: To investigate changes in emergency nursing workload related to cannabis ingestion or inhalation by adult and pediatric patients in states and bordering states where recreational cannabis is legal. Results: The legalization of recreational cannabis in some US states is reported as resulting in an increase in patients presenting with cyclic vomiting syndromes, and