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Conclusions: These results show that subacute exposure to amphetamines is associated with an advancement of cardiovascular-organismal age both over age and over time, and is robust to adjustment. That this is associated with power functions of age implies a feed-forward positively reinforcing exacerbation of the underlying ageing process. Download PDF  

Progression from first use to use disorder on alcohol, cannabis, stimulants, sedatives and opioids Highlights Pre-existing mental disorders increases the risk of developing SUD. Prior SUD increases the risk of transitioning from use to use disorder. Highest rates of transition to SUD occurred among stimulant and opioid users. Mood and anxiety disorders increased the risk of transitioning to AUD

There’s a figure that is often quoted by vaping enthusiasts: e-cigarettes are 5 per cent as harmful as traditional combustible cigarettes. That figure comes from Public Health England. But according to Dr Sarah White, director of Quit Victoria (part of the Cancer Council), this is a “spurious made up figure”. She says the constant quoting

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SUMMARY  Cannabis smoke contains many of the same carcinogens and chemicals found in tobacco smoke (Moir, Rickert et al. 2008, Wei, Alwis et al. 2016). Exposure to secondhand cannabis smoke can impair endothelial function, which increases the risk of cardiovascular disease (Wang, Derakhshandeh et al. 2016). However, US data show that the perceived health risks

The Institute for Behavior and Health is pleased to share with you an interview of IBH President Robert L. DuPont, MD featured in Opioid Watch of The Opioid Research Institute:  The Opioid Crisis is Now About Synthetics and Polydrug Use

Transmission of other bloodborne infections, particularly HIV and hepatitis B virus (HBV), is also increasing among injection-drug users, albeit at a slower rate. The opioid epidemic has also been linked to increasing rates of syphilis and other sexually transmitted infections, microbial endocarditis, and other infections associated with unsafe drug injection.3 The social and economic costs

JACC: Journal of the American College of Cardiology – Key Summary Patients aged ≤50 years presenting with their first myocardial infarction were retrospectively analyzed to evaluate the prevalence of cocaine and marijuana use and the impact on clinical outcomes. The prevalence of the use of cocaine and/or marijuana was 10.7%. Compared with patients without a

PREVENTION ALLIANCE Electronic cigarettes, or e-cigarettes, were invented in 2003 by Chinese inventor and pharmacist Hon Lik. Although many companies and advocates continue to bill them as a safer, smokeless alternative to traditional cigarettes, a U.S. Surgeon General report alarmingly found that 16% of high school students regularly use e-cigarettes. What’s worse, many young people who

March 6, 2018 – Abstract Naloxone access may unintentionally increase opioid abuse through two channels: (1) saving the lives of active drug users, who survive to continue abusing opioids, and (2) reducing the risk of death per use, thereby making riskier opioid use more appealing. By increasing the number of opioid abusers who need to