Isabella List Updates

CBD Not Recommended for Pain – Again (The placebo works)

Oral cannabidiol (CBD) as add-on to paracetamol for painful chronic osteoarthritis of the knee: a randomized, double-blind, placebo-controlled clinical trial. View PDF Background: Painful knee osteoarthritis (KOA) is common, pharmacological treatment, however, is often hampered by limited tolerability. Cannabidiol, which preclinically showed anti-inflammatory, analgesic activity, could supplement established analgesics, but robust clinical trials are lacking. The aim of our study was to investigate the

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Cannabidiol (CBD) products for pain: ineffective, expensive, and with potential harms

Published: October 18, 202 3DOI:https://doi.org/10.1016/j.jpain.2023.10.009 Highlights CBD products may have varying amounts of CBD, varying from none to much more than advertised. CBD products may contain other chemicals than CBD, some of which may be harmful. 16 RCTs for pain used pharmaceutical CBD in oral, buccal/sublingual, and topical forms. 15 of the 16 RCTs were

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Child Abuse – Girls a Particular Target. (The AOD Factor?)

The following two research papers that were released very recently, bring again to the public square the growing, and often lifelong harms, of child abuse.  Whilst these research offerings did not specifically look at contributing factors, the Dalgarno Institute continues to prompt a deeper look below the surface of these appalling statistics.  The ‘causal and

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F.A.S.D and the Impact of Alcohol Advertising: Protecting the Unborn

(F.A.S.D Day 9th of 9th 2023)Alcohol consumption during pregnancy has long been recognized as a significant health concern due to its potential to cause severe developmental issues in foetuses. Foetal Alcohol Spectrum Disorder (FASD) is a preventable brain disease that can affect a child’s lifelong health and well-being when a pregnant woman consumes alcohol.  Completely incurable –

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Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

(Summary:  the following demographics should completely ABSTAIN from cannabis use: People aged 0-28 years of age (children and adolescents – developing brain) Pregnant women People with mental illness or vulnerable to such Drivers/Driving (one could also assume, anyone operating a vehicle of any kind) Whilst there are only some minor benefits from some cannabis derivatives,

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Cannabis Use & Perinatal Health Research (JAMA)

…in utero cannabis exposure is linked to adverse outcomes among offspring, including small for gestational age, neonatal intensive care unit admissions, and preterm birth. In addition, prenatal cannabis exposure has also been associated with childhood outcomes such as autism spectrum disorder and attention-deficit/hyperactivity disorder, as well as symptoms of psychopathology, including psychotic like experiences, internalizing,

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‘Grown ups’ Substance use is a key ACE for Kids – Leading to Cannabis Use.

Adverse childhood experiences are ‘strong predictor’ for adolescent cannabis use. Young people who are exposed to adverse childhood experiences between the ages of 0 – 12 years, including parental drug misuse, are at highest risk for developing problematic adolescent cannabis use as teenagers, according to a new study. Adverse childhood experiences (‘ACEs’) considered included physical, emotional

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Building Resilience in Children Aged 9-13: A Most Effective Method of Illicit Drug Use Prevention

Building Resilience in Children Aged 9-13: A Most Effective Method of Illicit Drug Use Prevention #WorldResiliencyDay23 #WorldDrugDay It is no secret that illicit drug use is a major problem in our society. And the reasons for that are many. However, it is a growing irresilience and a careless drug use normalising ‘adult culture’ that model the

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