Isabella List Updates

CBD is Neurotoxic – Cannabidiol Impairs Brain Mitochondrial Metabolism and Neuronal Integrity

Summary: In conclusion, the present study describes the neurotoxicity of CBD above a defined concentration threshold and identifies a potential novel mechanism for this deleterious effect on the neuronal structure and function. Our results have significant implications for clinical utilization and public consumption of CBD and CBD containing products.Further investigations are necessary to firmly establish both the therapeutic

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Australia has a vaping problem, but no easy health or political solution – Or is there?

Regardless of the purported opinions and postures around the failing harm reduction ‘vehicle’ that is e-cigarettes, our children’s health, well-being and future should be the priority; motivating the political will to push the QUIT and PREVENTION mandates and mantras in all key Education, Legal and Social arenas.   The following excerpt from a recent ABC article is

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Adolescent Cannabis Use Really Messes with Brain Development.

Cannabis in Adolescence: Lasting Cognitive Alterations and Underlying Mechanisms Abstract: Cannabis consumption during adolescence is an area of particular concern, owing to changes in the social and political perception of the drug, and presents a scientific, medical, and economic challenge. Major social and economic interests continue to push toward cannabis legalization as well as pharmaceutical development.

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Clinical Epigenomic Explanation of the Epidemiology of Cannabinoid Genotoxicity Manifesting as Transgenerational Teratogenesis, Cancerogenesis and Aging Acceleration

Abstract (Excerpt): As global interest in the therapeutic potential of cannabis and its’ derivatives for the management of selected diseases increases, it is increasingly imperative that the toxic profile of cannabinoids be thoroughly understood in order to correctly assess the balance between the therapeutic risks and benefits. Modern studies across a number of jurisdictions, including Canada,

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Labelling of Cannabidiol (CBD) Products: A Public Health Perspective

Conclusions: Accurate and informative labelling of hemp and hemp-derived CBD products is an important public health issue. FDA-regulated product labels are considered an essential tool for protecting consumers and enabling informed decision-making. Untruthful or unsubstantiated health-related claims, and unallowed Drug Claims, in marketing materials and on labels of CBD products may create harm by enticing consumers

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Big Tobacco and Vaping Science – Who’s Researching What & Why?

Today February one, The Australian Newspaper release an article tiled, Exposed: big tobacco’s links to vape research. They report led with…“one of the world’s largest tobacco companies funded research into vapes and e-cigarettes that had positive findings and have since been promoted by Australian researchers”.The Australian went onto report that, Philip Morris infiltrated academia through the Foundation

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Male alcohol use may be a crucial, unrecognized factor affecting IVF outcomes

Texas A&M research highlights the need to expand pre-pregnancy messaging to emphasize the reproductive dangers of alcohol use by both parents. (TEXAS A&M UNIVERSITY)Research from Dr. Michael Golding’s laboratory at Texas A&M University indicates that male alcohol use has a significant negative influence on in vitro fertilization (IVF) success rates, thus increasing patient financial burden and

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Cannabis use produces persistent cognitive impairments

by Society for the Study of AddictionA systematic review published today in the scientific journal Addiction has found that cannabis use leads to acute cognitive impairments that may continue beyond the period of intoxication. This Canadian-led meta-review (review of reviews) merged the findings of 10 meta-analyses representing more than 43,000 participants.The study found that cannabis intoxication leads

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The Ever Increasing Harms of Continuing Drug Use: The addiction crisis is causing a spike in endocarditis cases. Hospitals are struggling to respond

  By Lev Facher Jan. 17, 2023   Increased injection drug use has led to a spike in cases of the life-threatening heart condition endocarditis, with cases rapidly accelerating since the onset of Covid-19.The increased case count is one of the lesser-known side effects of the deadly addiction epidemic. But patients with endocarditis, an inflammation of the heart

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Long-Term Outcomes of Adolescent THC Exposure on Translational Cognitive Measures in Adulthood in an Animal Model and Computational Assessment of Human Data

JAMA Psychiatry. Published online November 23, 2022.  doi:10.1001/jamapsychiatry.2022.3915Question  Is there an association between adolescent high-dose Ä9-tetrahydrocannabinol (THC) exposure and cognitive vulnerability in adulthood?Findings  In this rat model, high-dose THC exposure during adolescence resulted in risky decision-making and impulsivity in adulthood, similar to results from reanalyzed data from 37 human chronic cannabis users, an association enhanced by acute THC

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