Cannabis as Medicine

The toxicological profile of CBD raises safety concerns, especially for long term consumption by the general population. Highlights Potential hazards from long term oral use of CBD are discussed. CBD-induced male reproductive toxicity is observed from invertebrates to primates. Mechanisms of CBD-mediated oral toxicity are not fully understood. For full Research  Also see CBD & […]

JAMA Psychiatry. Published online May 3, 2023. doi:10.1001/jamapsychiatry.2023.0731 Abstract: Currently, only 4 cannabis products are approved for medicinal use. However, cannabis and cannabis products are widely promoted as therapeutic agents, placing potential burdens on physicians and other clinicians to recommend them, in the absence of sufficient clinical evidence, as treatments. The main aim of this Viewpoint

Source: (HealthDay News · May 14, 2023) Really? Who says? At What expense? Researchers funded by or tied to the Cannabis industry. “Several authors disclosed financial ties to the pharmaceutical and cannabis industries. Emyria funded the collection of data for this study.” It’s important to ask could all this perceived sense of ‘quality of life’ could be more

Summary: The prevalence of cannabis use in women of childbearing age is increasing drastically, likely related to increased legalization. Cannabis use during pregnancy is likely associated with preterm birth, low birth weight, and long-term neuropsychiatric outcomes, although data have significant limitations. Providers should screen for cannabis use and CUD regularly and counsel women about the known

The prevalence of cannabis use is rising among the US population.1 As cannabis continues to be legalized throughout the USA, people are turning to the internet and social media for information about its potential health benefits.2,3 In this study, we characterize internet claims about the health benefits of cannabis use in the lay press and evaluate the

Research Reveals…Of the 30 melatonin gummy brands meeting the inclusion criteria, 4 were unavailable for purchase and 1 did not contain “melatonin” on the actual label; therefore, 25 products were analyzed. One product did not contain detectable levels of melatonin but did contain 31.3 mg of CBD. In the remaining products, the quantity of melatonin

AbstractBackground: The mechanisms underlying the clinical effects of CBD remain poorly understood. Given the increasing evidence for CBD’s effects on mitochondria, we sought to examine in more detail whether CBD impacts mitochondrial function and neuronal integrity. Results: At low micromolar concentrations, CBD reduced mitochondrial respiration, the threshold for mitochondrial permeability transition, and calcium uptake, blocked a novel

Marijuana Is Not the Solution for PTSD — Evidence shows it does not treat PTSD in the long-term, and may worsen symptoms A growing number of states have identified post-traumatic stress disorder (PTSD) as an approved condition for medical marijuana. According to Colorado’s Medical Marijuana Registry, there are 70,533 patients as of February 2023 with an active

Potential birth defects, cancer and addiction – just name a few!Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog InteractionDOI: 10.1038/s41598-019-52336-w Abstract: We tested whether cannabinoids (CBs) potentiate alcohol-induced birth defects in mice and zebrafish, and explored the underlying pathogenic mechanisms on Sonic Hedgehog (Shh) signalling. The CBs, Ä9-THC, cannabidiol, HU-210, and CP 55,940 caused alcohol-like effects on craniofacial