Cannabis Conundrum

Cannabis Use & Congenital Abnormalities

Geospatiotemporal and Causal Inferential Study of European Epidemiological Patterns of Cannabis- and Substance-Related Congenital Orofacial Anomalies Conclusion. Rising cannabis use is associated with all the Facial Congenital Abnormalities and fulfils the epidemiological criteria for causality. The data indicate particular concerns relating to brain development and exponential genotoxic dose-responses, urging caution with regard to community cannabinoid

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Cannabis Effects on Driving Performance: Clinical Consideration

Key Points Driving under the influence of cannabis has been identified as a public health concern as medical and recreational cannabis availability increases in some countries. A recent randomized clinical trial found similar levels of acute driving impairment with THC-dominant cannabis and with a combination of THC-CBD equivalent cannabis using on-road driving tests that provided

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Cannabis use produces persistent cognitive impairments

by Society for the Study of AddictionA systematic review published today in the scientific journal Addiction has found that cannabis use leads to acute cognitive impairments that may continue beyond the period of intoxication. This Canadian-led meta-review (review of reviews) merged the findings of 10 meta-analyses representing more than 43,000 participants.The study found that cannabis intoxication leads

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Promoting Pot Increases Use – But Challenging Cannabis Harms, Shifts Attitudes Too.

Exposure to Pro and Anti-Cannabis Social Media Messages and Teens’ and College Students’ Intentions to Use Cannabis Content analyses have documented that posts about cannabis are increasingly common on social media. The relationship between the cannabis-related content to which teens and college students are exposed on social media and how such content may be associated

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Pediatric Hospitalizations for Unintentional Cannabis Poisonings and All-Cause Poisonings Associated With Edible Cannabis Product Legalization and Sales in Canada

JAMA Health Forum. 2023;4(1):e225041. doi:10.1001/jamahealthforum.2022.5041Key PointsQuestion  What is the association between legalization of recreational cannabis edibles and unintentional pediatric cannabis poisoning?Findings  This cross-sectional study of all children (n = 3.4 million) aged 0 to 9 years across 4 Canadian provinces found that jurisdictions that allowed the sale of cannabis edibles experienced much larger increases in cannabis poisonings and proportions of

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Long-Term Outcomes of Adolescent THC Exposure on Translational Cognitive Measures in Adulthood in an Animal Model and Computational Assessment of Human Data

JAMA Psychiatry. Published online November 23, 2022.  doi:10.1001/jamapsychiatry.2022.3915Question  Is there an association between adolescent high-dose Ä9-tetrahydrocannabinol (THC) exposure and cognitive vulnerability in adulthood?Findings  In this rat model, high-dose THC exposure during adolescence resulted in risky decision-making and impulsivity in adulthood, similar to results from reanalyzed data from 37 human chronic cannabis users, an association enhanced by acute THC

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Smoke and minors: Child marijuana use has soared 250% in last 20 years — replacing alcohol as the drug of choice for under-18s

The latest study involved nearly 340,000 reports to poison centers involving all drugs over 20 years. Researchers looked solely at those involving children aged six to 18. They found cases involving marijuana rose the quickest of any substance, replacing alcohol in 2014 and rising fastest between 2017 and 2020 — when weed began to be decriminalized at the federal

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Research shows cannabis use in adolescents linked with anxiety and memory loss

by Prabhjot Sohal, University of Western OntarioSchulich School of Medicine & Dentistry researchers have shown that chronic exposure during adolescence to tetrahydrocannabinol (THC), the main psychoactive component of cannabis, may induce long-lasting memory impairments and increased anxiety levels.The study, published in the journal Neuropsychopharmacology,NeuropsychopharmacologyThe study, published in the journal Neuropsychopharmacology, uses a rodent model to pinpoint two different parts

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