E-cigarette use among adolescents has become a widespread public health concern. Despite the known harms of nicotine exposure, there has been a lack of empirically tested interventions aimed at helping teens quit vaping. A recent randomised clinical trial investigated the effectiveness of a tailored, interactive text message program designed to promote vaping cessation among adolescents.
Study Design and Participants
The study was a parallel, two-group, double-blind, individually randomised clinical trial conducted from October 1, 2021, to October 18, 2023. It included 1,503 adolescent e-cigarette users aged 13 to 17 years who were interested in quitting vaping within 30 days. Participants were recruited via social media ads and were required to own a mobile phone with an active text message plan. The intervention was delivered via text message, and assessments were completed online or by telephone.
Interventions
Participants were divided into two groups:
- Assessment-Only Control Group (n=744): This group received only study retention text messages.
- Intervention Group (n=759): In addition to receiving study retention text messages, this group received a tailored, automated, interactive text message program designed to deliver cognitive and behavioural coping skills training and social support.
Primary Outcome Measure
The primary outcome of the study was self-reported 30-day point-prevalence abstinence from vaping at seven months. This was analysed using intention-to-treat analysis, with any missing data coded as continued vaping.
Results
The trial achieved a 70.8% retention rate at seven months. The intention-to-treat analysis revealed the following abstinence rates:
- Intervention Group: 37.8% of participants reported abstinence from vaping.
- Assessment-Only Control Group: 28.0% of participants reported abstinence from vaping.
This difference was statistically significant (P < .001). Importantly, no baseline characteristics, including nicotine dependence, moderated the treatment-outcome relationship. Additionally, there was no evidence that adolescents who quit vaping transitioned to combustible tobacco products.
Implications
The study demonstrated that a tailored, interactive text message program significantly increased self-reported vaping cessation rates among adolescents. This finding is crucial given the high prevalence of e-cigarette use among teens and the associated health risks. The success of this intervention highlights the potential of using digital health tools to support adolescent vaping cessation.
This randomised clinical trial provides strong evidence that a tailored text message program can effectively help adolescents quit vaping. Given the high rates of e-cigarette use among teens and the lack of empirically tested cessation interventions, this study underscores the importance of developing and implementing innovative digital health solutions to address this public health challenge.
(Source: JAMA)

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